For healthy men without significant underlying conditions, Vidalista is typically well-tolerated. Common side effects include headache, flushing, nasal congestion, indigestion, and muscle aches, which are usually mild and temporary. Serious side effects are rare but can include priapism (prolonged erection), sudden vision or hearing loss, and severe drops in blood pressure, especially when combined with nitrates or certain other medications. Men with cardiovascular disease, low blood pressure, severe liver or kidney issues, or those taking medications like nitrates should avoid Vidalista 80 unless specifically cleared by a physician. Additionally, improper use, such as exceeding the prescribed dose or combining Vidalista with recreational drugs or alcohol, can heighten health risks.